NFL Week 6 Computer Predictions, Best Bets, Over/Under Picks

Published 12:17 am Wednesday, October 9, 2024

What’s the best bet to make, looking at each of the 14 games on the NFL’s Week 6 schedule? Our favorite point-spread pick is Eagles -8.5, but we have lots more suggestions for you, which could lead to parlay opportunities, below.

Take advantage of our predictions to make your NFL picks this week. BetMGM has all the information you need to begin betting on the NFL.

Best Week 6 Spread Bets

Jump to Matchup:

Sign up for our daily email newsletter

Get the latest news sent to your inbox

IND-TEN | JAX-CHI | BUF-NYJ | LAC-DEN | PIT-LV

Pick: Titans +1 vs. Colts

  • Matchup: Indianapolis Colts at Tennessee Titans
  • Projected Winner & Margin: Colts by 0.6 points (Bet on this game at BetMGM)
  • Spread: Colts -1
  • Time: 1:00 p.m. ET
  • Date: Oct. 13
  • TV Channel: CBS
  • Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Bears -2.5 vs. Jaguars

  • Matchup: Jacksonville Jaguars vs. Chicago Bears
  • Projected Winner & Margin: Bears by 13.5 points (Bet on this game at BetMGM)
  • Spread: Bears -2.5
  • Time: 9:30 a.m. ET
  • Date: Oct. 13
  • TV Channel: NFL Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Jets +2.5 vs. Bills

  • Matchup: Buffalo Bills at New York Jets
  • Projected Winner & Margin: Jets by 3.2 points (Bet on this game at BetMGM)
  • Spread: Bills -2.5
  • Time: 8:15 p.m. ET
  • Date: Oct. 14
  • TV Channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Broncos +3 vs. Chargers

  • Matchup: Los Angeles Chargers at Denver Broncos
  • Projected Winner & Margin: Broncos by 6.4 points (Bet on this game at BetMGM)
  • Spread: Chargers -3
  • Time: 4:05 p.m. ET
  • Date: Oct. 13
  • TV Channel: CBS
  • Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Steelers -3 vs. Raiders

  • Matchup: Pittsburgh Steelers at Las Vegas Raiders
  • Projected Winner & Margin: Steelers by 8.7 points (Bet on this game at BetMGM)
  • Spread: Steelers -3
  • Time: 4:05 p.m. ET
  • Date: Oct. 13
  • TV Channel: CBS
  • Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Make smart decisions. Use those stats when making your NFL picks and place your bet on BetMGM.

Best Week 6 Total Bets

Jump to Matchup:

Over 41.5 – Buccaneers vs. Saints

Over 52.5 – Commanders vs. Ravens

  • Matchup: Washington Commanders at Baltimore Ravens
  • Projected Total: 54.3 points (Bet on this game at BetMGM)
  • Time: 1:00 p.m. ET
  • Date: Oct. 13
  • TV Channel: CBS
  • Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Under 35.5 – Chargers vs. Broncos

  • Matchup: Los Angeles Chargers at Denver Broncos
  • Projected Total: 31.7 points (Bet on this game at BetMGM)
  • Time: 4:05 p.m. ET
  • Date: Oct. 13
  • TV Channel: CBS
  • Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Under 49.5 – Cardinals vs. Packers

Under 52.5 – Lions vs. Cowboys

Catch every NFL touchdown with NFL RedZone on Fubo.

Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER.